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近年来,随着对抗Hp治疗的深入研究与临床实践,有效及合理的抗Hp治疗方案提高了消化性溃疡的治愈率,减少了溃疡的复发率。据多家报道,以奥美拉唑为基础的三联方案有确切的Hp根除率,其中常用的奥美拉唑、阿莫西林、克拉霉素三联组合其Hp根除效果>90%[2,3]。本组通过不同方案治疗消化性溃疡表明,二联疗法的Hp根除率与上述报道基本相似,溃疡愈合情况不尽如人意,而通过本组的观察进一步证实奥美拉唑、阿莫西林、克拉霉素三联方案不论是溃疡愈合、Hp根除,还是症状缓解率方面与二联组比较均差异有显著性(P<0.05)。
In recent years, with the in-depth research and clinical practice of anti-Hp treatment, effective and rational anti-Hp treatment program has improved the cure rate of peptic ulcer and reduced the recurrence rate of ulcer. According to several reports, the omeprazole-based triple regimen has an exact Hp eradication rate, of which omeprazole, amoxicillin, and clarithromycin are commonly used in combination with Hp eradication> 90% [2,3 ]. The group treated by different programs of peptic ulcer that Hp eradication rate of two combined therapy and the above reports are similar to the ulcer healing is not satisfactory, and further observation by this group confirmed that omeprazole, amoxicillin, carat The triple therapy regimen was significantly different (P <0.05) from ulceration healing, Hp eradication, or symptom response rate in the two groups.