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多发性肌炎(polymyositis,PM)现认为是自身免疫性疾病,除侵犯肌肉外,尚可有皮肤、心、肺及消化道的病变,然合并明确组织学异常之肝病者甚少见,文献只有12例报道,其中合并自身免疫性肝炎者仅3例。本文作者报道2例如下。例1:44岁,女性,每日饮威士忌1瓶达10年。40岁时曾有乏力、黄疸、肝脾肿大,血清转氨酶、絮浊度及其它肝胆系酶均升高,γ-球蛋白达31.6%,乙型肝炎表面抗原及抗体阴性,戒酒并给予保肝治疗后略有好转。次年患者出现进行性登梯困难,查血肌
Polymyositis (PM) is now considered to be an autoimmune disease. In addition to muscle involvement, there may be lesions of the skin, heart, lungs and digestive tract. However, there are few reports of liver diseases with clear histological abnormalities. Only 12 cases were reported, of which only 3 cases had autoimmune hepatitis. The authors report two cases as follows. Example 1: 44 years old, female, drink 1 bottle of whiskey daily for 10 years. 40 years old had fatigue, jaundice, hepatosplenomegaly, serum aminotransferase, turbidity and other hepatobiliary enzymes were elevated, γ-globulin reached 31.6%, hepatitis B surface antigen and antibody negative, abstinence and given Liver protection slightly improved after treatment. The following year patients with progressive boarding difficulties, check the blood muscle