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目的观察奥美拉唑对脑血管病并发上消化道应激性溃疡出血的疗效。方法 2003年2月～2006年4月在我院急诊科病房收治的急性脑血管病并发上消化道应激性溃疡出血患者50例,随机分为两组,在常规治疗基础上,治疗组25例予奥美拉唑40mg静滴,1次/d,对照组25例予西米替丁0.6g静滴,两组疗程均为3d。结果治疗组显效率为84%,总有效率为96%,对照组显效率为32%,总有效率为76%,两组比较均有显著性差异(P<0.01)。结论奥美拉唑治疗脑血管病并发上消化道应激性溃疡出血效果好,值得临床推广。
Objective To observe the curative effect of omeprazole on cerebrovascular disease complicated with upper gastrointestinal stress ulcer bleeding. Methods From February 2003 to April 2006, 50 patients with acute cerebrovascular disease complicated with upper gastrointestinal stress ulcer hemorrhage admitted to our emergency department ward were randomly divided into two groups. On the basis of routine treatment, the treatment group 25 Cases of omeprazole 40mg intravenous infusion, 1 / d, 25 cases of control group to cimetidine 0.6g intravenous infusion, two courses of treatment were 3d. Results The effective rate was 84%, the total effective rate was 96% in the treatment group, the effective rate in the control group was 32% and the total effective rate was 76%. There was significant difference between the two groups (P <0.01). Conclusion Omeprazole treatment of cerebrovascular disease complicated by upper gastrointestinal stress ulcer bleeding is worthy of clinical promotion.