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目的探讨体表胃电图参数与消化道相关症状之间的联系。方法选择肝硬化患者62例,其中A级为18例;B级为24例;C级为20例。同时选择20例正常志愿者为对照组。胃电图检测记录包括空腹及进食试餐后不同慢波节律的百分比、主频(DF)、主功率(DP)、餐后/餐前功率比(PR)几项数据,进行对比分析。计量资料采用配对t检验和单因素方差分析;组间比较采用最小显著差法(LSD)。结果①健康组、肝硬化组DF分别为3.0±0.21cpm、2.8±0.23cpm;DP分别为46.35±5.19dB、43.71±3.47dB;N%分别为49.23±12.71%、36.27±8.99%;PR分别为1.16±0.11、1.09±0.06。肝硬化组DF、DP、N%、PR平均值均低于对照组,有显著性差异。②肝硬化3组中N%分别为(41.08±5.96)%、(34.99±11.65)%、(33.48±5.59)%;Child-Pugh分级A级与B级、C级间有显著性差异。PR分别为1.12±0.02、1.09±0.04、1.05±0.07。Child-Pugh分级A、B、C三组中C级与A级间差异有统计学意义。结论①肝硬化组较对照组相比其DF、N%、PR明显下降,提示肝硬化患者存在胃电节律紊乱。②Child-Pugh分级A、B、C级三组N%、PR依次降低,证明肝脏的损害越重,其胃电异常改变越明显。
Objective To explore the relationship between surface electrogastrogram parameters and gastrointestinal symptoms. Methods Sixty-two patients with cirrhosis were selected, including 18 cases of A grade, 24 cases of B grade and 20 cases of C grade. At the same time select 20 normal volunteers as control group. Electrogastrogram detection records include fasting and eating a meal after different slow wave rhythm percentage, frequency (DF), the main power (DP), postprandial power ratio (PR) of several data for comparative analysis. Measurement data using paired t-test and one-way analysis of variance; comparison between groups using the least significant difference method (LSD). Results ① In DF group, DF were 3.0 ± 0.21cpm and 2.8 ± 0.23cpm respectively; DP were 46.35 ± 5.19dB and 43.71 ± 3.47dB respectively; N% were 49.23 ± 12.71% and 36.27 ± 8.99% respectively; 1.16 ± 0.11, 1.09 ± 0.06. The average values of DF, DP, N% and PR in cirrhosis group were lower than those in control group, with significant difference. ② The percentages of N in liver cirrhosis group were (41.08 ± 5.96)%, (34.99 ± 11.65)% and (33.48 ± 5.59)%, respectively. There was significant difference between Child-Pugh grade A and B, C grade. PR were 1.12 ± 0.02, 1.09 ± 0.04, 1.05 ± 0.07 respectively. Child-Pugh grading A, B, C three groups of C-level and A-level difference was statistically significant. Conclusion ① Compared with the control group, the levels of DF, N% and PR in cirrhotic patients were significantly decreased, suggesting that gastric electrical rhythm disturbances exist in cirrhotic patients. ②Child-Pugh grading A, B, C three groups of N%, PR decreased in turn, that the more severe liver damage, the more obvious abnormal changes in the stomach.