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目的一组随访13年的老年人死亡原因与代谢综合征之间关系的分析。方法回顾性分析1996年-2009年老年人群查体和病历资料,比较不同代谢性疾病对人群死亡率的影响。结果本组2 160例老年人在13年的随访中共死亡576例,总死亡率26.67%;死亡原因排位前三名的是恶性肿瘤、呼吸系统疾病及心血管疾病,分别占总死亡人数的36.98%、31.42%和18.23%;多因素回归分析显示年龄(OR=1.17,95%CI=1.144~1.193)和高血压(OR=1.39,95%CI=1.078~1.779)为死亡的独立危险因素。单个代谢疾病死亡率比较,仅高血压组死亡率(29.31%)高于非高血压组(19.80%,P<0.01),肥胖、糖、脂代谢异常组与对应非肥胖、非糖尿病、非高血压组死亡率相似。随着代谢综合征组分叠加,心、脑血管患病率显著增加,但死亡原因仍以恶性肿瘤及呼吸系统疾病为主。结论本组老年人群恶性肿瘤、呼吸系统疾病及心血管疾病为主要死亡原因,增龄及高血压增加老年人群死亡风险,代谢综合征组分叠加未增加死亡率。
AIM: To investigate the association between the causes of death and metabolic syndrome in a 13-year-old population. Methods A retrospective analysis of physical examination and medical history data of elderly people from 1996 to 2009 was conducted to compare the effects of different metabolic diseases on the mortality rate of the population. Results The group of 2 160 elderly patients died of 576 cases with a total mortality rate of 26.67% at 13-year follow-up. The top three causes of death were malignant tumors, respiratory diseases and cardiovascular diseases, accounting for the total number of deaths 36.98%, 31.42% and 18.23% respectively. Multivariate regression analysis showed that age (OR = 1.17, 95% CI = 1.144-1.19) and hypertension (OR = 1.39, 95% CI = 1.078-1.779) were independent risk factors for death . Compared with non-hypertension group (19.80%, P <0.01), the death rate of single metabolic disease group was significantly higher in hypertension group (29.31%) than in non-hypertension group and in non-obesity, non-diabetes, Mortality in the blood pressure group was similar. With the accumulation of metabolic syndrome components, the prevalence of cardiovascular and cerebrovascular diseases increased significantly, but the cause of death was still mainly malignant tumors and respiratory diseases. Conclusion The main causes of death are malignant tumors, respiratory diseases and cardiovascular diseases in this elderly population. Increasing age and hypertension increase the risk of death in the elderly population and the metabolic syndrome component does not increase the mortality rate.