机体对肿瘤的免疫应答反应处于低能状态 ,从而使肿瘤逃避免疫监视而发生、发展。肿瘤可通过多条途径使机体处于免疫功能低下或耐受状态 ,包括 :干扰树突状细胞的抗原提呈、阻碍T细胞的活化及免疫应答、自身抗原表达的异常、抗凋亡因子的作用、产生有利其生长的微环境等。对肿瘤免疫逃逸机理的研究有助于人们寻找和设计新的肿瘤免疫治疗方法和途径 The body’s response to tumor immune response in a state of low energy, so that the tumor escape immune surveillance and development. Tumors can cause the body to become immunocompromised or tolerant in several ways, including interfering with dendritic cell antigen presentation, blocking T cell activation and immune responses, autoantigen expression abnormalities, and anti-apoptotic factors , Resulting in the growth of its micro-environment and so on. Research on the mechanisms of tumor immune escape helps people to find and design new methods and approaches of tumor immunotherapy