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为探讨Epstein—Barr病毒(EBV)在急、慢性扁桃体炎患者中的感染情况及相互关系,采用聚合酶链反应(PCR)技术,对53例扁桃体炎症患者的唾液及组织标本内的EBV—DNA进行检测,同时用酶联免疫反应(ELISA)检测血清EBh壳抗原的免疫球蛋白C(IgC—VCA),并以正常人作为对照 结果扁桃体炎患者EBV—DNA的检出率明显高于正常人(P<0.05),提示EBV与扁桃体炎的发生、发展有一定的关系;而正常人与扁桃体炎患者的血清IgG—VCA检出率均在93％以上,提示两者对EBV呈高度易感性。
In order to investigate the Epstein-Barr virus (EBV) infection in acute and chronic tonsillitis patients and their relationship, using polymerase chain reaction (PCR) in 53 patients with tonsillitis in saliva and tissue samples of EBV-DNA (IgC-VCA) of serum EBh shell antigen was detected by enzyme-linked immunosorbent assay (ELISA), and the result of EBV-DNA detection was significantly higher in patients with tonsillitis than in normal subjects (P <0.05), suggesting that EBV has a certain relationship with the occurrence and development of tonsillitis. The detection rates of serum IgG-VCA in both normal and tonsillitis patients are all above 93%, suggesting that both of them are highly susceptible to EBV .