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目的探讨黄芪合用美托洛尔治疗扩张型心肌病(DCM)对心脏重塑及心功能改善的疗效。方法对DCM住院病人59例进行超声心动图(UCG)检测。随机分两组:黄芪治疗组30例,在常规治疗的基础上加用黄芪及β-受体阻滞剂。常规治疗组29例,均用强心、利尿、血管扩张剂,随访共6个月,统计6个月时的UCG结果。结果黄芪治疗组各指标比治疗前均有显著改善(P<0.05);常规治疗组亦有不同程度改善,但无统计学意义(P>0.05)。结论黄芪合用美托洛尔治疗DCM能有效地抑制心肌重塑,降低心脏重量,改善心功能。
Objective To investigate the curative effect of Astragalus combined with Metoprolol in the treatment of dilated cardiomyopathy (DCM) on cardiac remodeling and cardiac function improvement. Methods 59 cases of DCM inpatients were examined by echocardiography (UCG). Randomly divided into two groups: Astragalus treatment group 30 cases, on the basis of conventional treatment with astragalus and β-blockers. In the conventional treatment group, 29 cases were treated with cardiotomy, diuretic and vasodilator. All patients were followed up for 6 months. The UCG results at 6 months were statistically analyzed. Results Astragalus treatment group each index than before treatment were significantly improved (P <0.05); conventional treatment group also improved in varying degrees, but not statistically significant (P> 0.05). Conclusion Astragalus combined metoprolol in the treatment of DCM can effectively inhibit myocardial remodeling, reduce heart weight, improve cardiac function.