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目的分析2014年笔者所在医院药品不良反应(ADR)发生情况,深入探索讨论药品不良反应发生的原因。方法对2014年医院上报的397例ADR报告进行回顾性分析。结果 ADR病例男女比例为l:1.11;ADR发生于各个年龄组,<10岁年龄组中ADR病例占22.70%;一般或常见的ADR占73.80%;以静脉给药的方式引发的ADR为主,占82.87%;抗感染药物引起ADR为最多,占总数的74.31%;临床表现以皮肤及附属器官损伤最常见,占73.80%。结论合理规避引起ADR的临床因素,加强ADR监测工作,可促进合理用药,保障用药安全。
Objective To analyze the incidence of adverse drug reaction (ADR) in the hospital where the author was hospitalized in 2014 and explore the causes of adverse drug reactions in depth. Methods A retrospective analysis of 397 ADR reports reported by hospitals in 2014 was conducted. Results The ratio of male to female in ADR cases was 1: 1.11. ADR occurred in all age groups. ADR cases accounted for 22.70% in <10 years old group and 73.80% in common or common ADR cases. ADR induced mainly by intravenous administration, Accounting for 82.87%. Anti-infectives caused the most ADR, accounting for 74.31% of the total. The most common clinical manifestations were skin and accessory organs, accounting for 73.80%. Conclusion To reasonably avoid the clinical factors that cause ADR and to strengthen the monitoring of ADR can promote the rational use of drugs and ensure the safety of drugs.