本文报告1例美尼尔氏病作迷路切除病人的椭圆囊和内淋巴管近侧组织光镜及电镜观察结果。上皮从鳞状到柱状细胞变异较大,光镜看到衬于柱状上皮细胞的基底膜明显增厚,而电镜观察则见基底膜和邻接基底膜的血管有类似原纤维结构的病理性增厚。近年来各家对美尼尔氏病椭圆囊超微病理研究发现,感觉毛缺失,感觉细胞泡浆空泡化,感觉和支持细胞内有脂褐质堆积,以及与神经上皮基底部有关的细胞外间隙出现的胶原纤维沉积。但这些改变尚未能证实是否直接导致疾病或因年龄不同而表现出的非特异性变化。光镜检查内淋巴积水病人的球囊基底膜也增厚并呈环状凝集。本文介绍的病例,在椭圆囊、椭圆囊管和内淋巴管近侧部非感觉区内基底膜有病理变化,非常类 This article reports 1 case of Meniere’s disease for labyrinthine resection of patients with oval sac and proximal lymphatic tissue light microscopy and electron microscopy results. Epithelial squamous to columnar cells larger variation, the light microscope to see the basement membrane lining columnar epithelial cells was significantly thicker, while the electron microscope observation of the basement membrane and the adjacent basement membrane blood vessels have similar fibrillar pathological thickening . In recent years, various studies on the pathophysiology of Meniere’s disease showed that sensory hair loss, sensory vacuolar air bubbles, sensory and support cells with lipofuscin accumulation, and the base of the neural epithelium related cells Collagen fibers appear in the outer space. However, these changes have not been able to confirm whether the direct result of disease or non-specific changes shown by age. Light microscopy of endolymphatic fluid in patients with balloon basement membrane thickening and ring agglutination. This article describes the case, in the oval capsule, oval capsule and lymphatic proximal non-sensory area of ​​the basement membrane pathological changes, very category