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自从HP被分离培养成功以来,国内外学者应用血清学方法进行了许多流行病学方面的研究,即通过测定血清中HP抗体诊断HP感染。但血清学方法不能诊断HP现症感染,因为HP感染已根除较长时间后,血清中仍可检测出HP抗体,故阳性结果并不一定意味着存在HP现时感染,而~(13)C-UBT应用稳定同位素及质谱学技术,并非检测HP抗体,且诊断HP感染的灵敏性及特异性都在95％左右,如~(13)C-UBT结果阳性,一般即被认为存在HP感染。 本文应用~(13)C-尿素呼吸试验(~(13)C-UBT),检测了因上消化道症状而来我院就诊的1637例门诊病人,初步了解在不清楚胃镜检查结果的情况下,有上消化道症状病人的HP感染情况。
Since HP was successfully isolated and cultured, domestic and foreign scholars have carried out many epidemiological studies using serological methods, namely, the diagnosis of HP infection by measuring HP antibodies in serum. However, serological methods can not diagnose HP infection, because HP antibodies can still be detected in serum after a long period of eradication. Therefore, the positive results do not necessarily mean the presence of HP infection at present, but ~ (13) C- UBT application of stable isotope and mass spectrometry technology, not the detection of HP antibodies, and the diagnosis of HP infection sensitivity and specificity are about 95%, such as ~ (13) C-UBT positive results, generally considered to be HP infection. In this paper, ~ (13) C-urea breath test (~ (13) C-UBT), detected from the upper gastrointestinal symptoms in our hospital for treatment of 1637 cases of outpatients, a preliminary understanding of gastroscopy in the case of unclear , There is upper gastrointestinal symptoms of HP infection in patients.