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目的:总结尼日利亚翼状胬肉的治疗现状。方法:选择1999-01/2002-12的4a期间的翼状胬肉手术患者,所有病例都来自于尼日利亚Enugu市的尼日利亚大学教学医院和Ebrans临床中心。收集这些患者的生理数据、临床表现、手术方法和术后并发症等资料,应用6.1版EPI-INFO方法进行数据处理。共选择3种不同的手术方法:60眼单纯施行巩膜暴露术,42眼施行联合5-氟尿嘧啶(5-FU)的巩膜暴露术,22眼施行联合丝裂霉素C的巩膜暴露术。结果:72例(124眼)施行翼状胬肉切除术的患者,术后至少随访1a,包括男41例(56.9%),女31例(43.1%),男女比例为1∶0.8。术后复发率最高的在病变第III期(55.6%),最低在病变第I期(22.2%)。3种手术方法比较,复发率分别为65.0%、52%和13.6%。结论:在像尼日利亚这样的发展中国家,联合丝裂霉素的早期手术切除术,是一种安全性强、治疗费用低、方法简单且创伤小的治疗翼状胬肉的有效手段,值得推广。
Objective: To summarize the current situation of the treatment of pterygium in Nigeria. METHODS: Patients with pterygium surgery during the period 4a from January 1999 to December 2002 were selected, all from the Nigerian University Teaching Hospital in Enugu, Nigeria and the Ebrans Clinic. The physiological data, clinical manifestations, surgical methods and postoperative complications of these patients were collected and processed by EPI-INFO version 6.1. Three different surgeries were selected: scleral exposure alone in 60 eyes, scleral exposure in 42 eyes combined with 5-fluorouracil (5-FU), and scleral exposure in 22 eyes combined with mitomycin C. RESULTS: Totally 72 patients (124 eyes) underwent pterygium excision. The patients were followed up for at least 1 year. The results included 41 males (56.9%) and 31 females (43.1%), with a ratio of 1:08 males and females. Postoperative recurrence rate was highest in stage III (55.6%) and lowest in stage I (22.2%). The three surgical methods, the recurrence rates were 65.0%, 52% and 13.6%. CONCLUSIONS: In developing countries like Nigeria, early mitomycin-associated surgical resection is an effective, cost-effective, simple and less invasive treatment for pterygium, which is worthy of promotion.