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目的 调查上海市某社区卫生服务中心门诊患者抑郁障碍患病情况.方法 采取综合性医院焦虑抑郁量表(HADS)对门诊847名就诊者进行筛查,对于HADS抑郁亚量表评分≥8分患者采用中文版《简明国际神经精神访谈》(M.I.N.I.)筛查后,根据美国精神障碍诊断和统计手册第4版(DSM-Ⅳ)标准进行抑郁障碍诊断.结果 完成838人有效调查,295例(35.2％)患者HADS评分≥8分,16.1％(135/838)符合M.I.N.I.抑郁障碍诊断标准,其中重性抑郁发作检出率12.6％ (106/838)、心境恶劣检出率2.5％ (21/838)、双相抑郁检出率1.0％ (8/838).结论 社区卫生服务中心就诊患者中抑郁症状和抑郁障碍检出率较高,应引起重视以加强识别和诊治.“,”Objective To investigate the prevalence of depressive disorders in the outpatients of a community health service center in Shanghai.Methods Eight hundred and forty-seven outpatients were screened with the Hospital Anxiety and Depression Scale (HADS).Of the screened outpatients,the patients with depressive scale score of HADS ≥8 were assessed with the MINI international neuropsychiatric interview (M.I.N.I.) and made the diagnosis of depressive disorder according to the criteria of DSM-Ⅳ.Results Eight hundred and thirty-eight outpatients completed the effective investigation,and 295 (35.2％) outpatients had a HADS score ≥ 8.Of the enrolled 838 patients,16.1％ (135/838) met the criteria for depressive disorders with major depressive episode 12.6％ (106/838),dysthymia 2.5％ (21/838) and bipolar depression 1.0％ (8/838).Conclusion The prevalence rates of depressive symptoms and depressive disorders are high in the community health service center that deserved to be paid more attention for recognition,diagnosis and treatment.