目的探讨热毒宁治疗小儿疱疹性咽峡炎发热的临床效果。方法 2007年1月至2010年6月在我院小儿科接纳小儿疱疹性咽峡炎患者350例,一组给予头孢类药物抗感染,利巴韦林抗病毒治疗;一组在头孢类药物抗感染基础上给予热毒宁抗病毒治疗。结果观察组和对照组退热时间分别为(2.8±0.8)d和(4.2±0.9)d,经SPSS 13.0统计软件统计分析,差异有统计学意义(P<0.05)。对照组显效率、总有效率分别为68.8%、81.8%,观察组显效率、总有效率分别为79.4%、93.3%,观察组的疗效优于对照组,差异有统计学意义(P<0.05)。结论热毒宁可以明显缩短小儿疱疹性咽峡炎发热时间,减少患者痊愈时间。 Objective To investigate the clinical efficacy of Renduining in the treatment of fever in children with herpes simplex angina. Methods From January 2007 to June 2010, 350 cases of pediatric herpes simplex angina were admitted to our hospital for pediatric patients. One group was given anti-infective cephalosporins and ribavirin antiviral therapy. One group was given anti-infectives of cephalosporins On the basis of heat poisoning anti-virus therapy. Results The antipyretic time in the observation group and the control group were (2.8 ± 0.8) d and (4.2 ± 0.9) d, respectively, and the difference was statistically significant (P <0.05) by statistical software SPSS 13.0. The effective rate and total effective rate of the control group were 68.8% and 81.8% respectively. The effective rate and total effective rate of the observation group were 79.4% and 93.3% respectively. The curative effect of the observation group was better than that of the control group (P <0.05 ). Conclusion Revedoxin can significantly shorten the time of fever in children with herpes angina and reduce the time of recovery.