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目的:观察兰索拉唑、莫沙必利两药联合对胆汁反流性胃炎的疗效。方法:胆汁反流性胃炎患者随机分为4组:空白对照组(n=50)、兰索拉唑(n=50,兰索拉唑20mg,1次/d),莫沙必利组(n=50莫沙必利1.0g,3次/d)及联合用药组(n=50,兰索拉唑+莫沙必利,用法同上),疗程8周。观察各组患者腹痛、腹胀、烧心、口苦等症状改善情况。结果:治疗后三组治疗组患者症状均有所改善。结论:兰索拉唑和莫沙必利联用可有效治疗胆汁反流性胃炎。
Objective: To observe the efficacy of lansoprazole and mosapride in combination with bile reflux gastritis. Methods: The patients with bile reflux gastritis were randomly divided into 4 groups: blank control group (n = 50), lansoprazole (n = 50, lansoprazole 20 mg once a day), mosapride group n = 50 mosapride 1.0g, 3 times / d) and combination group (n = 50, lansoprazole + mosapride, usage ibid.) for 8 weeks. All patients were observed abdominal pain, bloating, heartburn, mouth pain and other symptoms to improve the situation. Results: The symptoms of the three treatment groups improved after treatment. Conclusion: Combination of lansoprazole and mosapride can effectively treat bile reflux gastritis.