致病疫霉可引起马铃薯和番茄晚疫病,常造成巨大损失,生产中主要依靠抗病品种和化学农药防治。但因病菌生理分化明显、遗传变异迅速,已出现能克服现有全部抗病基因的菌株,且抗药性日益突出,致使该病难以完全有效地得到控制。发掘致病疫霉颉颃微生物,并研发安全、高效的微生物农药是当前的研究热点之一。结合笔者开展的研究工作,就近年来国内外对致病疫霉颉颃细菌的筛选、颉颃物质及其作用机制等进行了综述。同时,对该领域当前存在的一些问题和今后的研究重点进行了讨论,以期加快对致病疫霉颉颃细菌的利用。 Phytophthora infestans can cause late blight in potatoes and tomatoes, often resulting in huge losses. Production mainly depends on disease-resistant varieties and chemical pesticides. However, due to the obvious physiological differentiation of the bacteria, the genetic variation is rapid. Strains that can overcome all existing disease-resistance genes have emerged and the resistance is increasingly prominent, making it difficult to control the disease completely and effectively. It is one of the hotspots to find out the pathogenic fungi antagonistic microorganisms and to develop safe and efficient microbial pesticides. In the light of the research work carried out by the author, the screening of antagonistic pathogens such as Phytoplankton in the world at home and abroad in recent years, the mechanism of antagonistic substances and their mechanisms are reviewed. At the same time, some existing problems in the field and the future research priorities are discussed with a view to accelerating the utilization of Phytophthora infestans.