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目的:研究鹿茸提取物对东莨菪碱及亚硝酸钠所致小鼠学习记忆障碍的影响。方法:小鼠连续灌胃鹿茸提取物15D后,对东莨菪碱及亚硝酸钠造成学习记忆障碍的小鼠进行“Y”型电迷宫行为学检测,结果在“Y”型电迷宫行为学检测中,鹿茸提取物用药组小鼠学习记忆成绩较模型组均有显著提高(P< 0．05)。结论:鹿茸提取物对东莨菪碱及亚硝酸钠造成的两种学习记忆障碍小鼠的学习记忆能力均有明显的改善作用。
Objective: To study the effects of pilose antler extract on learning and memory impairment of mice induced by scopolamine and sodium nitrite. METHODS: After mice were continuously fed with antler extract 15D, mice with learning and memory impairment caused by scopolamine and sodium nitrite were subjected to “Y”-type electric maze behavioral tests. The results were in the “Y”-type electric maze behavioral tests. The learning and memory scores of mice treated with pilose antler extract were significantly higher than those of the model group (P<0.05). Conclusion: The antler extracts can significantly improve the learning and memory abilities of mice with learning and memory impairment caused by scopolamine and sodium nitrite.