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冠状动脉病变是晚期肾脏疾病患者存活的重要决定因素,作者对六年随诊的36例接受慢性血液透析治疗和23例肾移植受者进行了~(201)Tl负荷试验预后估价的研究。~(201)Tl负荷试验“即刻”和“再分布”显像〔74MBq TlCl/(潘生丁0.5mg·kg~(-1)),静注〕是在空腹状态下进行的。血液透析患者中~(201)Tl负荷试验异常的18例为第一组(平均年龄58±11岁),其中只有33%的患者有冠状动脉病变的临床表现;~(201)Tl负荷试验正常的18例为第二组(平均年龄45±11岁)。两组患者接受血液透析的时间大致相同(第一组为38±11个月,第二组为35±26个月)。据所知,所有患者都有冠状动脉病变的高危险因素。
Coronary artery disease is an important determinant of survival in patients with advanced renal disease. We evaluated the prognostic value of ~ (201) Tl load trials in 36 patients who underwent chronic hemodialysis and 23 renal transplant recipients over six years of follow-up. Immediate loading and redistribution of the Tl load test (74 MBq TlCl / 0.5 mg kg -1 dipyridamole) were performed in the fasting state. Among the hemodialysis patients, 18 patients with ~ (201) Tl load test were abnormal in the first group (mean age 58 ± 11 years), and only 33% of them had clinical manifestations of coronary artery disease. The ~ (201) Tl load test was normal 18 cases of the second group (mean age 45 ± 11 years). The duration of hemodialysis was approximately the same for both groups (38 ± 11 months in the first group and 35 ± 26 months in the second group). It is known that all patients have a high risk of coronary artery disease.