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目的:探讨瑞芬太尼和芬太尼对小儿麻醉的血流动力学影响,以为临床用药提供参考依据。方法:选取2013年1月至2014年1月于我院进行手术的100例ASA I至Ⅲ级患儿为研究对象,依循随机平均分配原则将其分为对照组和观察组,对照组应用芬太尼进行麻醉,观察组给予瑞芬太尼施以麻醉,比较两组患者血流动力学改变各项指标、拔管时间及语言应答时间。结果:比较两组患者各项血流动力学改变指标,观察组患者血流动力学较之于对照组而言,稳定性更高,差异显著,具有统计学意义(P<0.05);比较两组患者术后拔管所需时间以及语言应答所需时间,观察组拔管时间和语言应答时间显著短于对照组,比较差异具有统计学意义(P<0.05)。结论:瑞芬太尼较之于芬太尼,其应用于小儿麻醉中,对于患儿的血流动力学指标影响较小,且麻醉苏醒时间短,安全性高,具推广意义。
Objective: To investigate the hemodynamic effects of remifentanil and fentanyl on pediatric anesthesia in order to provide a reference for clinical use. Methods: From January 2013 to January 2014, 100 ASA I to III children undergoing surgery in our hospital were selected as the research objects. According to the principle of random equal distribution, they were divided into control group and observation group. The control group was treated with Fen Tai Nai anesthesia, the observation group was given remifentanil anesthesia, hemodynamic changes in both groups were compared indicators, extubation time and language response time. Results: Compared with the control group, the haemodynamics in the observation group was significantly higher than that in the control group (P <0.05) The time required for extubation and the time required for language response in the group of patients were significantly shorter than those in the control group (P <0.05). The extubation time and language response time in the observation group were significantly shorter than those in the control group. Conclusion: Remifentanil compared with fentanyl, which is used in pediatric anesthesia, has little effect on hemodynamics in children and has short anesthesia recovery time and high safety, which is of great significance.