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作者用双丁酰环磷腺苷(dibutyryl cAMP,DBcAMP)治疗51例烫伤、外伤和各种皮肤疾病引起的皮肤溃疡,获得了满意的结果。将DBcAMP 300mg用注射用水溶解,配制成1.12 M的DBcAMP溶液,可在冰箱内保存1周。用0.05%葡萄糖酸洗必太溶液或聚烯吡酮碘每日1次局部消毒后,再用0.12MDBcAMP喷洒疮面。局部可涂抹白色凡士林,但不并用其他皮肤溃疡治疗剂。治疗时间10天～6个月。结果治愈率78%(40/51),11例无变化或中止治疗。治愈速度加快而无迁延治愈的病例。治愈的40例患者中,有30例未出现肥厚性瘢痕。形成肥厚性瘢痕的10例患者,瘢痕均较轻,可用类固醇硬膏、海绵压迫
The authors used dibutyryl cAMP (dibutyryl cAMP, DBcAMP) treatment of 51 cases of scalds, trauma and various skin diseases caused by skin ulcers, and obtained satisfactory results. DBcAMP 300mg dissolved in water for injection to prepare a 1.12 M DBcAMP solution, can be stored in the refrigerator for 1 week. 0.05% gluconate washed with too solution or povidone-iodine once daily local disinfection, and then spraying 0.12MDBcAMP sore surface. Partially white Vaseline can be applied, but not with other skin ulcer treatment. Treatment time 10 days to 6 months. Results The cure rate was 78% (40/51). No change or discontinuation was found in 11 patients. Cure faster without delay in the case of cure. Of the 40 patients who were cured, hypertrophic scars did not occur in 30 of the 40 patients. Hypertrophic scars formed in 10 patients with mild scars, available steroid plaster, sponge pressure