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目的:探讨阿奇霉素在慢性阻塞性肺疾病(COPD)肺炎衣原体(Cpn)慢性感染临床治疗中的应用价值。方法:选取2010年1月至2010年12月来我院接受慢性阻塞性肺疾病肺炎衣原体慢性感染患者60例,随机平分为观察组和对照组,其中对照组患者采用常规治疗方法进行治疗,观察组患者在对照组患者治疗的基础上使用阿奇霉素进行药物治疗,分别以两组患者的肺功能、超敏C反应蛋白水平、Cpn-IgG和Cpn-IgA水平作为观察指标,并使用SPSS 13.0软件包进行统计学分析。结果:观察组患者治疗后的肺功能明显优于对照组,P<0.05;观察组患者治疗后的超敏C反应蛋白水平、Cpn-IgG和Cpn-IgA水平均明显优于对照组患者,P<0.05。结论:在常规治疗的基础上使用阿奇霉素可有效的改善COPD患者肺功能,对于Cpn感染的改善和COPD的治疗均具有重要意义,具有推广应用价值。
Objective: To investigate the clinical value of azithromycin in the treatment of Chronic Obstructive Pulmonary Disease (COPD) chronic infection with Chlamydia pneumoniae (Cpn). Methods: From January 2010 to December 2010 in our hospital to accept chronic obstructive pulmonary disease Chlamydia pneumoniae patients with chronic infection 60 patients were randomly divided into observation group and control group, in which the control group of patients treated by conventional treatment, observation The patients in the control group were treated with azithromycin on the basis of the treatment of the patients in the control group. Pulmonary function, high-sensitivity C-reactive protein level, Cpn-IgG and Cpn-IgA levels of the two groups were taken as the observation indexes and SPSS 13.0 software package Statistical analysis. Results: The pulmonary function of the observation group was significantly better than that of the control group after treatment (P <0.05). The levels of Hs-CRP, Cpn-IgG and Cpn-IgA in the observation group were significantly better than those in the control group <0.05. Conclusion: The use of azithromycin on the basis of routine treatment can effectively improve pulmonary function in patients with COPD, which is of great significance for the improvement of Cpn infection and the treatment of COPD, and has the value of popularization and application.