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苏云金芽孢杆菌对多种昆虫具有特异毒杀作用,虽然对其作用机理有了一定的了解,但对昆虫随之出现的抗性研究还很不深入。利用秀丽隐杆线虫这种模式动物并结合基因芯片技术和基因组学研究,为详细了解苏云金芽孢杆菌毒素的作用机理、昆虫对毒素的抗性机理和研究更加高效的生物杀虫制剂提供了新的思路。
Bacillus thuringiensis has specific toxic effects on many kinds of insects. Although it has a certain understanding of its mechanism of action, the research on the subsequent emergence of insects is still not deep. The use of this model organism in C. elegans combined with gene chip technology and genomics studies provides new insights into the mechanism of action of B. thuringiensis toxins, the resistance mechanisms of insects to toxins and the development of more efficient biopesticides Ideas.