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目的探讨降钙素原(PCT)在判断系统性红斑狼疮(SLE)合并感染病原菌中临床价值。方法采用回顾性研究,选取2011年1月~2013年6月在我院住院的SLE合并感染患者98例。比较各种病原菌与PCT浓度的相关性,计算SLE合并感染革兰氏阴性菌、革兰氏阳性菌、真菌及支原体、病毒患者的PCT浓度。结果 SLE合并感染病原体的PCT浓度:革兰氏阴性菌组>革兰氏阳性菌组>真菌及支原体组>病毒组。结论 SLE合并感染病原菌与降钙素原水平有一定的相关性,定量检测PCT可辅助诊断SLE合并感染病原菌种。
Objective To investigate the clinical value of procalcitonin (PCT) in judging the pathogens of systemic lupus erythematosus (SLE) complicated by infection. Methods A retrospective study was conducted to select 98 patients with SLE complicated infection admitted to our hospital from January 2011 to June 2013. The correlation between various pathogenic bacteria and PCT concentration was compared to calculate the PCT concentration of SLE patients infected with Gram-negative bacteria, Gram-positive bacteria, fungi, mycoplasmas and viruses. Results The PCT concentrations of SLE co-infected pathogens: Gram-negative bacteria> Gram-positive bacteria> Fungal and mycoplasma> virus. Conclusion There is a certain correlation between pathogens and procalcitonin levels in SLE patients. Quantitative detection of PCT can be used to diagnose SLE pathogens.