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【目的】探讨维持性血液透析患者心脏瓣膜钙化对心律失常发生的影响。【方法】选择2012～2013年本院肾内科收治的110例维持性血液透析患者，平均年龄（56±11）岁，男性60例，女性50例，透析时间（1．2±0．62）年。依据超声心动图检查结果有无心脏瓣膜钙化将其分为观察组（35例）和对照组（75例）。随访6个月，观察两组患者心律失常发生情况。【结果】观察组房颤、房室传导阻滞的发生率显著高于对照组，差异具有统计学意义（ P ＜0．05），两组间早搏及其它心律失常（预激综合征、窦缓、窦速、房扑等）发生率比较差异无统计学意义（ P ＞0．05）。【结论】维持性血液透析患者合并心脏瓣膜钙化，易发生心律失常，且以传导阻滞型和房颤型心律失常为主。“,”[Objective] To explore the effect of cardiac valve calcification on arrhythmias in maintenance hemodialysis patients .[Methods] A total of 110 maintenance hemodialysis patients were recruited from neph‐rology department at our hospital from 2012 to 2013 .There were 60 males and 50 females with a mean age of 56 ± 11 years and a mean hemodialytic duration of 1 .2 ± 0 .62 years .According to the results of echocardio‐graphy with or without cardiac valve calcification ,they were divided into observation ( n=35) and control ( n=75) groups .During a mean follow‐up period of 6 months ,the incidence of arrhythmias was observed .[Re‐sults] The observation group had significantly higher incidences of atrial fibrillation and atrioventricular con‐duction block than those in the control group ( P 0 .05) .[Conclusion]Maintenance hemodialysis patients with valve calcification are prone to arrhyth‐mias .And atrial fibrillation and conduction block are more common .