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目的:探讨了糖尿病患者红细胞镁、蛋白酪氨酸磷酸酶(PTP)和血糖的关系.方法: 用葡萄糖氧化酶法和放免法分别测定30例糖尿病患者(DM)和20例正常对照组(NT)空 腹血糖(FGP)胰岛素浓度(FINS),等离子体原子发射光谱法测定红细胞镁,酶联免疫法测 定红细胞胞浆PTP活性、结果:DM组年龄,体重和体重指数(BMI)与NT组相比无显著性; 年龄(岁):(57.33 ± 7.21vs(58,35±7,71);体重(kg);(61.00±8.29)vs(61.95±6.96); BMI(kg· m~(-2)):(23.50± 2.50)vs( 2340± 2.70);收缩压(kPa):(16,41± 0.95vs (6.76 ± 0.98);舒张压(kPa):(9.96 ± 0.66)VS(10.28 ± 0.73),DM组FGP和PTP活性显 著高于NT组(FG(mmol·L~(-1)):(10.03±2.01)vs(5.16±0.70),P<0.001;PTP活性 (U):(8.40±1.99) vs(6.17± 2.84), P〈 005); DM组红细胞镁显著低于 NT组(Mg (umol·g~(-1))(5.48± 0.66) v
Objective: To investigate the relationship between erythrocyte magnesium, protein tyrosine phosphatase (PTP) and blood glucose in diabetic patients. Methods: Fasting blood glucose (FPS) insulin concentration (FINS) was measured in 30 diabetic patients (DM) and 20 normal controls (NT) by glucose oxidase and radioimmunoassay. Plasma magnesium oxide The results showed that the age, weight and body mass index (BMI) of DM group were not significantly different from those of NT group (57.33 ± 7.21 vs 58.35 ± (61.00 ± 8.29) vs (61.95 ± 6.96); BMI (kg · m -2) :( 23.50 ± 2.50 ) Vs (2340 ± 2.70); systolic blood pressure (kPa) :( 16,41 ± 0.95 vs (6.76 ± 0.98); diastolic blood pressure (kPa) :( 9.96 ± 0.66) VS (10.28 ± 0.73). The activities of FGP and PTP in DM group were significantly higher than those in NT group (FG (Mmol·L -1) :( 10.03 ± 2.01) vs (5.16 ± 0.70), P <0.001; PTP activity (U) :( 8.40 ± 1. 99) vs (6.17 ± 2.84), P <005). The level of magnesium in erythrocytes in DM group was significantly lower than that in NT group (5.48 ± 0.66) vs Mg (umol · g -1)