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目的:血管扩张刺激磷蛋白(VASP)是PKA的重要作用底物,它参与调节肌动蛋白丝的组装和集聚,但血管扩张刺激磷蛋白磷酸化在细胞移动中的确切作用及PKA如何将细胞外信号特异性传递到血管扩张刺激磷蛋白进而引起细胞迁移的具体调控机制尚不明确。本研究探讨激酶A锚定蛋白(AKAPs)对PK
AIM: Vasodilator-stimulated phosphoprotein (VASP) is an important substrate for PKA and is involved in the assembly and assembly of actin filaments. However, the exact role of vasodilator in stimulating phosphoprotein phosphorylation in cell migration and how PKA modulates cells Specific signal transduction to the vasodilator to stimulate phosphoproteins and further cell migration caused by the specific regulatory mechanism is not yet clear. This study investigated the effects of kinase A-anchored proteins (AKAPs) on PK