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目的:分析大环内酯类抗菌药物序贯疗法对肺炎支原体感染患者慢性咳嗽的临床疗效。方法:选取2013年1月—2015年12月间治疗的肺炎支原体抗体(MP-Ig M)阳性感染慢性咳嗽患儿163例,将其分为观察组(82例)和对照组(81例);观察组患者均给予大环内酯类药物序贯疗法治疗,对照组患者均给予阿奇霉素治疗,比较两组患者治疗后的总有效率和MP-Ig M转阴的总转阴率。结果:观察组患者治疗后的总有效率为97.56%高于对照组为86.42%(P<0.05);MP-Ig M总转阴率为96.34%高于对照组为83.95%(P<0.05)。结论:采用大环内酯类抗菌药物序贯疗法治疗肺炎支原体抗体(MP-Ig M)阳性感染慢性咳嗽患儿的临床疗效优于阿奇霉素的治疗。
Objective: To analyze the clinical effect of sequential therapy of macrolide antibiotics on chronic cough in patients with Mycoplasma pneumoniae infection. Methods: A total of 163 children with chronic cough were selected from January 2013 to December 2015 and were divided into the observation group (82 cases) and the control group (81 cases) . Patients in the observation group were treated with sequential macrolide therapy. Patients in the control group were treated with azithromycin. The total effective rate and the total negative conversion rate of MP-Ig M negative were compared between the two groups. Results: The total effective rate of the observation group after treatment was 97.56% higher than that of the control group (86.42%, P <0.05). The total negative conversion rate of MP-Ig M was 96.34% . Conclusion: The sequential treatment of macrolide antibiotics for the treatment of Mycoplasma pneumoniae antibody (MP-Ig M) positive chronic infection in children with clinical efficacy than azithromycin treatment.