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帕金森病(PD)是常见于中老年人群的第二大神经变性疾病,它的4大临床主症表现为静止性震颤、强直、运动迟缓和姿势反射障碍。在我国大于65岁以上人群中的PD患病率为1·7%,与欧美发达国家持平[1]。PD的神经病理变化已较明确,表现为残存神经元胞浆内路易小体(LB)形成、胶质增生和
Parkinson’s disease (PD) is the second most common neurodegenerative disease in the middle-aged and elderly population. Its four major clinical manifestations are resting tremor, ankylosis, bradykinesia, and postural reflexes. The prevalence of PD among people over 65 years old in China is 1.7%, which is in line with developed countries in Europe and the United States [1]. PD neuropathological changes have been more clear, manifested as residual neurons in the cytoplasm of Lewy bodies (LB) formation, glial proliferation and