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目的探讨内镜下黏膜切除术治疗结肠腺瘤临床疗效。方法选取2016年2月至2017年2月间山东省青岛市市立医院收治的82例结肠腺瘤患者,采用随机数表法分为研究组和对照组,每组41例。研究组患者采用内镜下黏膜切除术治疗,对照组患者采用常规内镜下电凝电切手术治疗,比较两组患者的手术时间、住院时间、完全切除率、并发症发生情况及肿瘤切除情况。结果研究组患者手术时间和住院时间均明显低于对照组,差异均有统计学意义(均P<0.05)。研究组患者完全切除率约97.6%,显著高于对照组的75.6%,差异有统计学意义(P<0.05)。研究组患者术中出血和穿孔发生率低于对照组,差异均有统计学意义(均P<0.05)。肿瘤切除情况比较可知,研究组患者残留率为4.9%,明显优于对照组的31.7%,差异有统计学意义(P<0.05)。结论内镜下黏膜切除术治疗结肠腺瘤,有较高的安全性和可靠性,肿瘤完全切除率较高,残留率较低,值得临床推广。
Objective To investigate the clinical efficacy of endoscopic mucosal resection in the treatment of colorectal adenoma. Methods A total of 82 patients with colonic adenoma admitted to Qingdao Municipal Hospital from February 2016 to February 2017 were randomly divided into study group and control group with 41 cases in each group. Patients in the study group were treated with endoscopic mucosal resection. Patients in the control group were treated by conventional endoscopic electrocoagulation and resection. The operation time, hospitalization time, complete resection rate, complications and tumor resection were compared between the two groups . Results The operation time and hospital stay of the study group were significantly lower than those of the control group (all P <0.05). The complete resection rate of the study group was 97.6%, which was significantly higher than that of the control group (75.6%), the difference was statistically significant (P <0.05). The incidence of intraoperative hemorrhage and perforation in study group was lower than that in control group, with significant differences (all P <0.05). The tumor resection shows that the residual rate of the study group was 4.9%, which was significantly better than that of the control group (31.7%), the difference was statistically significant (P <0.05). Conclusion Endoscopic mucosal resection of colorectal adenoma has high safety and reliability, high complete resection rate and low residual rate, which is worthy of clinical promotion.