目的　探讨吸毒母亲所生新生儿的临床特点及治疗措施。　方法　分析 5 4例吸毒母亲所生新生儿临床特点 ,并就相关治疗措施疗效和转归进行评价。　结果　 1990～ 2 0 0 2年 12年间我科共收治吸毒母亲新生儿 5 4例 ,其中早产儿 2 8例 ,低出生体重儿 32例 ,新生儿窒息 14例 ,新生儿呼吸窘迫综合征 (NRDS) 12例 ,颅内出血 8例 ,先天畸形 2例。 5 4例中 16例患儿均有不同程度的新生儿戒断综合征表现 ,2 9例出现低血钙、低血糖等内环境紊乱。其中母亲吸毒 2年以上组中早产、低出生体重、窒息及NRDS的发生率明显高于吸毒 2年以下组。经止惊、维持水电解质平衡及对症支持治疗 ,5 4例中 4 4例 (81% )症状控制出院 ,8例 (15 % )死亡 ,2例 (4 % )放弃治疗出院。　结论　吸毒对于新生儿危害极大 ,早产、低出生体重、窒息、NRDS等发生率与吸毒时间密切相关。综合治疗有助于患儿康复。 Objective To explore the clinical features and treatment of newborns born to drug addicts. Methods The clinical features of 54 newborns born to drug addicts were analyzed. The curative effect and prognosis of related treatment measures were evaluated. Results In 1990 to 2002, 54 cases of newborns with drug-using mothers were admitted to our department. Among them, 28 were premature infants, 32 were low birth weight infants, 14 were neonatal asphyxia, neonatal respiratory distress syndrome (NRDS ) In 12 cases, 8 cases of intracranial hemorrhage, 2 cases of congenital malformations. In 5 4 cases, 16 children had different degrees of neonatal withdrawal syndrome, 29 cases had hypokalemia, hypoglycemia and other internal environment disorders. Among them, the incidence of preterm birth, low birth weight, asphyxia and NRDS in mothers taking drugs for more than 2 years was significantly higher than that of those under 2 years of drug abuse. Four cases (81%) of 54 cases were discharged after the symptoms were controlled, 8 cases (15%) died, and 2 cases (4%) were given up their treatment and discharged. Conclusion Drug abuse is extremely harmful to the newborn. The incidence of premature birth, low birth weight, asphyxia and NRDS are closely related to the time of taking drugs. Comprehensive treatment helps children recover.