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目的分析内蒙古自治区2012—2014年脊髓灰质炎(脊灰)病毒分离和鉴定情况,为维持中国无脊灰状态提供依据。方法对来源于急性弛缓性麻痹病例、接触者和健康儿童的粪便标本进行病毒分离和型内鉴定,确定血清型别后进行VP1区核苷酸序列测定,并对结果进行分析。结果从1176份粪便标本中分离到脊灰病毒21株,非脊灰肠道病毒83株。21株脊灰病毒中1株为疫苗衍生脊灰病毒,其余20株为疫苗株,未发现脊灰野病毒。结论 2012—2014年内蒙古自治区继续维持无脊灰状态。
Objective To analyze the isolation and identification of poliomyelitis (polio) virus from 2012 to 2014 in Inner Mongolia Autonomous Region, and to provide evidence for the maintenance of polio-free status in China. Methods The stool samples from acute flaccid paralysis, contact and healthy children were isolated and identified in the virus. The serotypes were determined and the nucleotide sequence of VP1 was determined. The results were analyzed. Results 21 poliovirus strains and 83 non-polio enterovirus strains were isolated from 1176 stool specimens. One of 21 poliovirus was vaccine-derived poliovirus, and the remaining 20 were vaccine strains, no poliovirus was found. Conclusion Inner Mongolia Autonomous Region continues to maintain a polio-free status during 2012-2014.