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目的观察T细胞斑点试验在结核性胸膜炎诊断中的应用价值。方法选取结核性胸膜炎患者54例为观察组,同期确诊为非结核性胸腔积液患者50例为对照组。所有患者均采用T细胞斑点试验、血清结核抗体(TB-AB)、腺苷脱氨酶(ADA)、胸腔积液结核分枝杆菌培养检测,比较各个检测方法诊断准确情况。结果观察组斑点形成细胞(SFC)形成数量均高于对照组,差异有统计学意义(P<0.05);观察组抗原检测SFC阳性率均高于对照组,差异有统计学意义(P<0.05);T细胞斑点试验诊断准确率高于其他检测方法,差异有统计学意义(P<0.05)。结论 T细胞斑点试验用于临床诊断结核性胸膜炎具有极高的敏感度、特异度,诊断准确率高。
Objective To observe the value of T cell dot test in the diagnosis of tuberculous pleurisy. Methods Fifty-four patients with tuberculous pleurisy were selected as the observation group. Fifty patients diagnosed as non-tuberculous pleural effusion in the same period were selected as the control group. All patients were tested by T cell spot test, TB-AB, ADA and pleural effusion Mycobacterium tuberculosis, and the diagnostic accuracy of each test method was compared. Results The number of speckle forming cells (SFC) in the observation group was significantly higher than that in the control group (P <0.05). The positive rate of SFC in the observation group was higher than that in the control group (P <0.05) ). The diagnostic accuracy of T cell dot test was higher than other test methods, the difference was statistically significant (P <0.05). Conclusion The T-cell stain test is highly sensitive, specific and diagnostic accuracy for clinical diagnosis of tuberculous pleurisy.