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在防治冠心病的研究工作中,探索防治高脂血症的有效措施是一项重要课题。因为高脂血症是发生冠心病的重要条件之一。苏联学者MRCHИKOB,A,Л曾在人身上观察到给予大量维生素丙可降低高胆固醇血症病人血清胆固醇水平,同样在动物身上也观察到大剂量维生素丙可减轻喂胆固醇的家兔高胆固醇血症及动脉粥样,硬化程度。后来又研究发现,在给动物致动脉粥样硬化饲料同时给予C~(14)标记的胆固醇,发现胆固醇沉积于主动脉壁,但若同时给维生素丙,胆固醇则见于肝脏及肾上腺、而不在主动脉。有人观察到青年人服用维生素丙后血清胆固醇水平下降,而动脉粥样硬化病人血清胆固醇水平则升高,从而认为是由于
In the prevention and treatment of coronary heart disease research, to explore effective measures to prevent and treat hyperlipidemia is an important issue. Because of hyperlipidemia is one of the important conditions of coronary heart disease. The Soviet scholar MRCHИKOB, A, Л who have been observed in large doses of vitamin C can reduce the serum cholesterol levels of patients with hypercholesterolemia, the same animals are also observed in large doses of vitamin C can reduce hypercholesterolemia in cholesterol-fed rabbits And atherosclerosis, degree of hardening. Later found that, in animal atherosclerosis feed at the same time given C ~ (14) labeled cholesterol and found that the accumulation of cholesterol in the aortic wall, but if at the same time to vitamin C, cholesterol is found in the liver and adrenal glands, not the main artery. It has been observed in young people taking vitamin C serum cholesterol decreased, while atherosclerosis serum cholesterol levels are elevated, so that is due to