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目的验证上海科兴药业公司提供的89SrCl2注射液治疗转移性骨肿瘤所致骨痛的疗效。方法试验采用随机、双盲、阳性药物(英国Amersham公司生产的Metastron)对照,5个中心参加验证。对90例原发病灶诊断明确的恶性肿瘤骨转移患者进行骨痛镇痛治疗,其中资料完整的Ⅰ组(验证组)59例,Ⅱ?
Objective To verify the efficacy of 89SrCl2 injection provided by Shanghai Kexing Pharmaceutical Company in the treatment of bone pain caused by metastatic bone tumors. METHODS: A randomized, double-blind, positive drug (Metastron, Amersham, UK) was used for the trial. Five centers participated in the validation. Totally 90 patients with primary malignant tumor diagnosed with bone metastasis were treated with painless analgesia. Among them, 59 patients in group Ⅰ (validation group)