口腔鳞癌是口腔颌面部常见的一种恶性肿瘤。临床上主要采用手术治疗。可是,一些晚期患者术后常常局部复发或全身转移。因此,目前大多数学者主张综合治疗,如术前化疗或术后辅助放疗。采用术前化疗治疗鳞癌,可以提高肿瘤的切除率,减少远处转移,延长患者的无痛生存期。化疗的疗效受肿瘤的分期、部位、化疗方案和疗程的影响,目前仍处于探索阶段。近年来,肿瘤治疗的第四种疗法——生物治疗异 Oral squamous cell carcinoma is a common malignant tumor in oral and maxillofacial region. Clinically, the main surgical treatment. However, some patients with advanced disease often local recurrence or systemic metastasis. Therefore, at present, most scholars advocate comprehensive treatment, such as preoperative chemotherapy or postoperative adjuvant radiotherapy. The use of preoperative chemotherapy for squamous cell carcinoma, can improve tumor resection rate, reduce distant metastasis, prolong the painless survival of patients. The efficacy of chemotherapy is affected by the staging, location, chemotherapy regimen and course of treatment, and is still under exploration. In recent years, the fourth treatment of cancer treatment - different biological treatment