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目的探讨小剂量多巴胺治疗新生儿重症肺炎疗效。方法将符合新生儿重症肺炎诊断标准的新生儿随机分成治疗组(53例)和对照组(47例),对照组按常规吸氧、镇静、抗生素、超声雾化等治疗。治疗组在常规治疗的基础上加用多巴胺6mg/kg溶于5%葡萄糖50ml静脉滴注,可予小剂量2μg·kg·-1min-1,连用3d,比较两组患儿症状及体征。结果治疗组在应用小剂量多巴胺治疗新生儿重症肺炎,在症状体征的改善、吸氧时间、住院天数均较对照组明显缩短。结论小剂量多巴胺静脉滴注治疗新生儿重症肺炎,可迅速改善新生儿重症肺炎症状、体征,减少给氧时间,缩短住院天数,明显提高新生儿重症肺炎疗效。
Objective To investigate the efficacy of low-dose dopamine in the treatment of neonatal severe pneumonia. Methods Neonates with diagnostic criteria of severe neonatal pneumonia were randomly divided into treatment group (n = 53) and control group (n = 47). Patients in control group were treated with routine oxygen inhalation, sedation, antibiotics and ultrasonic atomization. On the basis of conventional treatment, the treatment group was given dopamine 6mg / kg dissolved in 50ml of 5% dextrose 50ml for a small dose of 2μg · kg · -1min-1 for 3 days. The symptoms and signs of the two groups were compared. Results The treatment group in the application of low-dose dopamine treatment of neonatal severe pneumonia, the improvement in symptoms and signs, oxygen inhalation time, hospitalization days were significantly shorter than the control group. Conclusion Intravenous infusion of small doses of dopamine in the treatment of severe pneumonia in neonates can rapidly improve the symptoms and signs of severe neonatal pneumonia, reduce the oxygenation time, shorten the length of stay in hospital and significantly improve the efficacy of neonatal severe pneumonia.