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近年来虽已肯定奎尼丁可增加地高辛的血浓度,但尚未仔细研究由此而出现的临床洋地黄中毒表现的发生率。为了评价奎尼丁对洋地黄毒性的作用影响,作者用波士顿联合药物监测方案
Although it has been confirmed in recent years that quinidine can increase the blood concentration of digoxin, the incidence of clinical digitalis poisoning has not yet been carefully studied. In order to evaluate the effect of quinidine on the toxicity of digitalis, the authors used the Boston Joint Drug Surveillance Program