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目的观察尼莫地平对脑出血血肿体积及脑水肿的临床疗效。方法选取80例患者随机将其分为两组,治疗组与对照组,对照组采用常规治疗,治疗组患者分别在发病后12h、48h及5d时给予静脉滴注尼莫地平8mg,治疗15d。分别对两组患者记录其入院时,5d及15d时的血肿体积及水肿带面积。结果治疗组患者相对对照组患者脑出血水肿带明显较小,尼莫地平能有效减轻患者脑出血水肿带出现程度。结论尼莫地平对治疗脑出血血肿体积及脑水肿的临床效果很好,12h内效果更好。
Objective To observe the clinical effect of nimodipine on hematoma volume and cerebral edema of intracerebral hemorrhage. Methods Eighty patients were randomly divided into two groups. The treatment group and the control group were given conventional treatment. The patients in the treatment group were given nimodipine 8 mg intravenously at 12h, 48h and 5d respectively after the onset of disease for 15 days. The volume of hematoma and the area of edema on the 5th and 15th day after admission were recorded respectively. Results Compared with control group, patients in treatment group had significantly smaller cerebral hemorrhage and edema zone, and nimodipine could effectively reduce the degree of cerebral hemorrhage edema zone. Conclusion The clinical effect of nimodipine on the treatment of intracerebral hemorrhage volume and cerebral edema is very good, the effect is better within 12h.