ADM为惠环类广谱抗肿瘤药，是我科治疗胃癌、乳腺癌主要的化学药物。但由于骨髓和心脏毒性累积作用而造成部分患者未能完成全部化疗，被迫停药，影响疗效。从1996年7月开始采用新型葱环类化合物毗柔比星（THP），其抗肿瘤作用无明显差异，而心肌毒性、胃肠道及脱发等毒副作用明 ADM is a broad-spectrum anti-tumor Cyclocynum, our department is the treatment of gastric cancer, breast cancer, the main chemical drugs. However, due to the cumulative effect of bone marrow and cardiac toxicity caused by some patients failed to complete the chemotherapy, was forced to stop the drug, affecting the curative effect. From July 1996 onwards, the new onion ring compound psoriumbromide (THP), no significant difference in its anti-tumor effect, and myocardial toxicity, gastrointestinal and other toxic side effects hair loss