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蒽环类药物是一类来源于波赛链霉菌青灰变种的化疗药物,是细胞周期非特异性的细胞毒性药物,作为目前治疗儿童白血病、淋巴瘤及多种实体肿瘤的一线化疗药物,具有广泛的抗肿瘤效应.但蒽环类药物引起的不良反应如心脏毒性、骨髓抑制、脱发等,尤其是心脏毒性,往往呈进展性且具有不可逆性,极大地影响了患儿的远期生活质量.对蒽环类药物心脏毒性早期发现、诊断及相应干预是目前临床心脏损害的研究热点.临床上用于监测蒽环类药物心脏毒性的方法很多,如何有效监测葸环类药物所致心脏毒性显得尤为重要.该文针对蒽环类药物所致心脏毒性评价方面的研究进展作一综述.“,”Anthracyclines are a class of chemotherapeutic drugs derived from Streptomyces faecalis,which are non-specific cytotoxic drugs in the cell cycle.They are widely used as fast-line chemotherapeutic drugs for the treatment of childhood leukemia,lymphoma,solid tumors and have a broad anti-tumor effect.However,side effects caused by anthracyclines included cardiotoxicity,myelosuppression,alopecia,etc,especially cardiotoxicity is often progressive and irreversible,strongly affecting the long-term quality of life of children.The early detection,diagnosis and corresponding intervention of anthracycline-induced cardiotoxicity are the research hotspots of clinical heart damage.There are many methods for monitoring the anthracycline-induced cardiotoxicity.How to effectively monitor the anthracycline-induced cardiotoxicity is particularly important.This article reviews the progress about the evaluation of anthracycline-induced cardiotoxicity.