目的　探讨丙型肝炎病毒血清学分型的可行性。方法　应用EIA法对兰州地区 148例抗 HCV阳性者进行血清学分型。结果　血清学方法的分型率为 5 6 0 8% (83 148) ,其中血清 1型占5 0 6 0 % (4 2 83) ,血清 2型占 43 37% (36 83) ,1+2混合型占 6 0 3% (5 83)。对其中 70例HCVRNA阳性血清的基因型与血清型结果进行比较 ,二者完全相符。结论　丙型肝炎病毒的血清学分型具有一定的临床应用价值 Objective To investigate the feasibility of serological typing of hepatitis C virus. Methods EIA was used to determine the serotypes of 148 anti-HCV positive individuals in Lanzhou. Results The serological typing rate was 56.08% (83 148). Serum type 1 accounted for 56 06% (4283), serotype 2 43% (36 83), serological type 1 + 2 Mixed accounted for 6 0 3% (5 83). The genotypes and serotypes of 70 HCV RNA positive sera were completely matched. Conclusion Serological typing of hepatitis C virus has certain clinical value