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目的:探讨托特罗定与坦索罗辛治疗泌尿系结石术后放置双J管所致下尿路症状的临床效果。方法:抽取苏州大学附属常熟医院2015年6月至2017年6月收治的泌尿系结石术后放置双J管具有下尿路症状的患者140例，采用随机数字表法分为研究组和对照组，每组70例。研究组采用托特罗定治疗，对照组采用坦索罗辛治疗。比较两组治疗前后的膀胱过度活动症状评分(OABSS)、输尿管相关症状问卷评分(USSQ)、国际前列腺症状评分(IPSS)、最大尿流率、残余尿量及最大排尿压。结果:治疗前，两组OABSS、USSQ及IPSS评分比较差异未见统计学意义(n P>0.05)；治疗后，两组OABSS、USSQ及IPSS评分均较治疗前降低(n P均0.05). After treatment, the OABSS, USSQ and IPSS score of the two groups were significantly lower than those before treatment (n P<0.05). The OABSS, USSQ score, and IPSS score of the study group were significantly lower than those of the control group after treatment (n P0.05). After treatment, the residual urine volume of the study group was lower than that of the control group (n P<0.05), while the maximum urinary flow rate and the maximum urinary pressure of the study group were higher than those of the control group (n P0.05.n Conclusions:Tolterodine has a better therapeutic effect than tamsulosin in the treatment of lower urinary tract symptoms induced by placing double-J stent after urolithiasis surgery.