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目的探讨新生儿高胆红素血症的病因及相关因素,为临床提供早诊断早治疗的依据。方法采取回顾性调查方法对90例新生儿高胆红素血症病因进行综合分析。结果新生儿高胆红素血症的病因以围产因素为主,占43.3%,葡萄糖-6磷酸脱氢酶(G-6PD)缺乏占18.0%,ABO溶血病占15.3%,感染占14.0%,原因不明占9.4%。其中发病日龄在生后7d内占84.7%。围产期因素所致新生儿高胆红素血症的发病率高于其他致病因素,差异有统计学意义(P<0.05)。治愈75例(83.3%),好转11例(12.2%),自动出院4例(4.4%)。结论对于新生儿高胆红素血症应早期诊断,寻找病因,以光疗为主的综合治疗预后良好。
Objective To explore the etiology and related factors of neonatal hyperbilirubinemia and provide the basis for early diagnosis and early treatment of clinical. Methods A retrospective survey of 90 cases of neonatal hyperbilirubinemia causes a comprehensive analysis. Results The causes of neonatal hyperbilirubinemia were mainly perinatal factors (43.3%), G-6PD deficiency (18.0%), ABO hemolytic disease (15.3%) and infection (14.0% , Unexplained account for 9.4%. Including the onset of age 7 days after birth accounted for 84.7%. The incidence of neonatal hyperbilirubinemia due to perinatal factors was higher than other risk factors, the difference was statistically significant (P <0.05). 75 cases were cured (83.3%), 11 cases (12.2%) were improved and 4 cases were discharged (4.4%) automatically. Conclusion For neonatal hyperbilirubinemia should be diagnosed early to find the cause, the comprehensive treatment with phototherapy prognosis is good.