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目的探讨卡维地洛治疗慢性心力衰竭的疗效及对心功能的影响。方法将我院80例慢性心力衰竭患者随机分为治疗组及对照组,对照组采用常规支持治疗,治疗组在对照组基础上加用卡维地洛。结果两组患者较治疗前心功能均有明显改善,治疗组改善情况优于对照组,差异有统计学意义(P<0.05)。治疗组出现低血压2例,窦性心动过缓1例,经过对症处理后均得到改善。结论卡维地洛与常规抗心衰药物联合应用治疗慢性心力衰竭,能有效减轻心脏重塑和改善心功能,疗效较好,安全性高,值得推广。
Objective To investigate the efficacy of carvedilol in treating chronic heart failure and its influence on cardiac function. Methods 80 cases of chronic heart failure in our hospital were randomly divided into treatment group and control group. The control group was treated with conventional supportive therapy. The treatment group was given carvedilol on the basis of the control group. Results Compared with the control group, the improvement of cardiac function in both groups was significantly improved before treatment, the difference was statistically significant (P <0.05). In the treatment group, there were 2 cases of hypotension and 1 case of sinus bradycardia, all of which were improved after symptomatic treatment. Conclusion Carvedilol and conventional anti-heart failure drugs combined treatment of chronic heart failure, can effectively reduce cardiac remodeling and improve cardiac function, efficacy, safety, and worth promoting.