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目的:研究对尿毒症患者进行高通量透析治疗对其心功能的影响。方法 :对2012年12月~2015年3月在我院进行维持性血液透析且病情稳定的48例尿毒症患者的临床资料进行回顾性分析,随机将其分为实验组和对照组,每组各24例患者。对实验组患者进行高通量透析治疗,对对照组患者进行低通量透析治疗,并对比分析两组患者在进行治疗12个月后其心功能指标及临床指标的变化情况。结果:与对照组患者相比,实验组患者在进行血液透析治疗后其心功能指标较优,差异显著(P<0.05),有统计学意义。与对照组患者相比,实验组患者在进行血液透析治疗后其P3+、PTH、BNG、β2微球等指标明显较低,差异显著(P<0.05),有统计学意义。结论 :对尿毒症患者进行高通量透析治疗可有效改善其炎症状态及贫血、营养不良等情况,保护其心脏功能,此法值得在临床上推广应用。
OBJECTIVE: To study the effect of high-throughput dialysis on cardiac function in uremic patients. Methods: The clinical data of 48 patients with uremia who underwent maintenance hemodialysis in our hospital from December 2012 to March 2015 were retrospectively analyzed. They were randomly divided into experimental group and control group, and each group Each 24 patients. The patients in the experimental group were treated with high-throughput dialysis and the patients in the control group were treated with low-flux dialysis. The changes of cardiac function and clinical indexes of the two groups after 12 months of treatment were analyzed. Results: Compared with the control group, the patients in the experimental group had better cardiac function after hemodialysis treatment, with significant difference (P <0.05). Compared with control group, the indexes of P3 +, PTH, BNG and β2 microspheres in experimental group were significantly lower after hemodialysis treatment, with significant difference (P <0.05). Conclusion: High-throughput dialysis treatment for patients with uremia can effectively improve their inflammatory status and anemia, malnutrition, etc., to protect their heart function, this method deserves to be widely applied in clinic.