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益康唑(Econazole)化学名为1-[2-(2,4-二氯苯基)-2-(4-氯苄氧基)-乙基]-咪唑硝酸盐,化学结构为: 本品是一种新的广谱、高效、副作用少的抗真菌药物,并兼有灰黄霉素、制霉菌素、青霉素三药的抗菌作用。据报道,3077例皮肤癣菌及皮肤念珠菌临床中,以本品1％含量的不同剂型外用,经1～32周治疗,治愈率为91.3％,进步率7.5％,无效1.2％。对3227例阴道念珠菌感染的治愈率达89.9％。治疗过程未见过敏反应和耐药性,仅有极少数病例患部产生红痒和烧灼感。本品的合成工艺国外未见有完整的资料报道,我们根据其化学结构和原料来源情况,自行
Econazole chemical name is 1- [2- (2,4-dichlorophenyl) -2- (4-chlorobenzyloxy) -ethyl] -imidazole nitrate, the chemical structure of: This product Is a new broad-spectrum, high efficiency, less side effects of anti-fungal drugs, and both griseofulvin, nystatin, penicillin antibacterial effect. It is reported that 3077 cases of dermatophytes and cutaneous candidiasis clinical application of 1% of the dosage form of the topical, after 1 to 32 weeks of treatment, the cure rate was 91.3%, the rate of progress 7.5%, 1.2% invalid. 3227 cases of vaginal candidiasis cure rate of 89.9%. No allergic reaction and drug resistance were observed in the course of treatment, and only a few cases of affected parts had itching and burning sensation. The synthesis of this product has not been reported abroad, a complete information, we based on their chemical structure and the source of raw materials, on their own