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目的 :比较不同疏肝中药对应激小鼠免疫功能影响。方法 :建立小鼠应激模型 ,观察柴胡 ;柴胡、黄芩 ;柴胡、白芍 ;柴胡、黄芩、白芍等四组疏肝中药对淋巴细胞增殖反应、T细胞亚群、白细胞介素 2 (interleukin 2IL 2 )活性。结果 :束缚应激后小鼠脾淋巴细胞增殖反应受抑制 ,成熟T淋巴细胞减少 ,其中T辅助细胞减少 ,T抑制细胞增多 ;IL 2活性降低。结论 :不同疏肝中药可对抗应激所致的免疫功能下降 ,疏肝清热养肝的柴、芩、芍组作用优于疏肝养肝之柴、芍组与疏肝清肝之柴、芩组 ,单纯疏肝的柴胡组的作用较弱
Objective : To compare the effects of different soothing liver herbs on immune function in stress mice. METHODS: A mouse stress model was established to observe the effects of Radix Bupleuri, Radix Bupleurum, Radix Astragali, Radix Bupleuri, Radix Paeoniae Rubra, Radix Bupleuri, Radix Astragali, Radix Paeoniae Alba, etc. on lymphocyte proliferation, T cell subsets, and leukocyte. 2 (interleukin 2IL 2 ) activity. RESULTS : After restraint stress, the proliferation of spleen lymphocytes in mice was inhibited and the number of mature T lymphocytes was decreased. T helper cells decreased and T suppressor cells increased. IL 2 activity decreased. Conclusion: The different liver-removing Chinese herbs can reduce the immune function caused by stress, and the effects of Shugan Qingre Yanggan on Chai, Fuling, and Fuling are superior to those of Shugan, Ganshao and Shugan Qinggan. Group, the role of simple liver-relieving Bupleurum group is weak