服用神经阻滞剂抗精神病药偶可出现一组严重的副反应称为神经阻滞剂恶性综合征(Neuroleptic malignant syndfome,NMS)。1960年首由Deley和Lempériér等报告,其后陆续见于法文文献中。70年代始受到日本、美国精神病学界的重视。在世界范围内迄今已有百余例报导,我国仅有2例报告。 NMS的临床特征为持续性高热、肌肉僵直、意识改变以及植物神经障碍所致的严重心血管症 Taking a nerve blocker antipsychotic even occasionally a group of serious side effects known as nerve blocker malignant syndrome (Neuroleptic malignant syndfome, NMS). First reported by Deley and Lempériér in 1960 and later in French literature. 70s began to Japan, the United States psychiatry attention. To date, more than 100 cases have been reported in the world and only 2 cases have been reported in our country. The clinical features of NMS are persistent fever, muscle stiffness, altered consciousness, and severe cardiovascular disease due to autonomic disorders