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目的探讨早期先天性梅毒脏器损害的临床特点,提高早期诊疗水平。方法对2011年1月—2013年7月收治的24例早期先天性梅毒患儿的临床资料进行回顾性分析,总结其临床特征。结果 24例患儿中,皮肤损害者15例(63%),肝脏损害者14例(58%),血液系统损害者11例(46%),肺脏损害者7例(29%),消化系统损害者6例(25%),心脏损害者3例(12%),肌肉骨骼损害者2例(8%),神经系统损害者2例(8%),多脏器损害者19例(79%)。结论早期先天性梅毒临床表现多样,可引起多个脏器损害,对不明原因的皮疹、肝功损害、贫血、发热、腹胀等临床表现的小儿应引起重视,及时进行筛查先天性梅毒,以利于该病早期诊断和治疗。
Objective To investigate the clinical features of early congenital syphilis organ damage and improve the level of early diagnosis and treatment. Methods The clinical data of 24 cases of early congenital syphilis admitted from January 2011 to July 2013 were retrospectively analyzed and the clinical features were summarized. Results Of the 24 children, 15 (63%) had skin lesions, 14 (58%) had liver damage, 11 (46%) had hematological damage, 7 (29%) had lung damage, (25%), 3 (12%) cardiac damage, 2 (8%) musculoskeletal damage, 2 (8%) neurological damage, and 19 %). Conclusions The early clinical manifestations of congenital syphilis are diverse and can cause damage to multiple organs. Children with clinical manifestations such as unexplained rash, liver damage, anemia, fever and abdominal distention should pay attention to timely screening for congenital syphilis. Benefit from the early diagnosis and treatment of the disease.