论文部分内容阅读
目的了解新疆和田农村地区60岁以上维吾尔族人群慢性阻塞性肺疾病(COPD)的患病率及危险因素,为防治慢性阻塞性肺疾病提供科学依据。方法 2009年4月28日～5月30日,采用按自然村整群随机抽样的方法,抽取维吾尔族聚集地新疆和田地区的部分县中户籍登记60岁以上的维吾尔族常住村民(≥5年)为调查对象,实际调查371名,资料完整的342人分为COPD组(78人)和非COPD组(264人),分别对其进行流行病学问卷、体格检查(包括身高、胸围、腹围、体重、皮脂厚度等)及肺功能检测。结果 COPD患病率达22.8%,男性为12.3%,女性为10.5%。不同年龄、不同性别患病率差异均无统计学意义(P>0.05);单因素分析显示,BMI、厨房无通气设备、慢性咳嗽咳痰(≥3个月)、肺功能值FEV1、FEV1%预计值、FEV1/FVC%等因素在COPD组和非COPD组相比差异有统计学意义(P<0.05);多因素逐步回归分析显示,厨房无通气设备(OR=0.553,95%CI=0.332～0.949,P<0.05)、低BMI(OR=4.179,95%CI=1.276～13.691,P<0.05)、喘息症状(OR=2.302,95%CI=1.263～4.196,P<0.05)是COPD的独立危险因素。结论该地区COPD患病率明显高于其它地区,厨房无通气设备、低BMI、咳嗽咳痰伴随喘息是新疆农村地区维吾尔族老人COPD高发病的独立危险因素,应针对危险因素采取综合干预措施降低发病率。
Objective To understand the prevalence and risk factors of chronic obstructive pulmonary disease (COPD) in Uyghurs over 60 years old in rural Hetian, Xinjiang, and provide a scientific basis for the prevention and treatment of chronic obstructive pulmonary disease. Methods From April 28, 2009 to May 30, 2009, Uygur resident villagers aged 60 or above who were registered in some counties in the Hetian area, where the Uyghur people gathered, were sampled (≥ 5 years) by random sampling in a cluster of villages. The survey was conducted on 371 subjects and 342 subjects with complete data were divided into COPD group (78 persons) and non-COPD group (264 persons), and their epidemiological questionnaires, physical examination (including height, chest circumference, abdominal circumference , Body weight, sebum thickness, etc.) and pulmonary function tests. Results The prevalence of COPD was 22.8%, 12.3% in males and 10.5% in females. Univariate analysis showed that BMI, no ventilator in the kitchen, chronic cough and sputum (≥3 months), pulmonary function FEV1, FEV1% Predictors, FEV1 / FVC% and other factors were significantly different between COPD group and non-COPD group (P <0.05). Multivariate stepwise regression analysis showed that there was no ventilator in the kitchen (OR = 0.553, 95% CI = ~ 0.949, P <0.05), low BMI (OR = 4.179, 95% CI = 1.276-13.691, P <0.05) and wheeze (OR = 2.302, 95% CI = 1.263-4.1966, P <0.05) Independent risk factors. Conclusions The prevalence of COPD in this area is obviously higher than that in other areas. There is no ventilator in the kitchen, low BMI and cough and phlegm accompanied with wheezing are independent risk factors for COPD in elderly in Xinjiang Uygur. Comprehensive interventions should be taken to reduce the risk factors Incidence.